My guess for today is that Pollard, a second RB (Malik Davis, Ronald Jones, or Zeke/another FA), Vaughn, and Luepke all make the team. That's a high number, but with Luepke's versatility, maybe the team decides it can go lighter at TE (3, not 4).
If the above turned out to be true, I wouldn't have a problem with Zeke taking the Davis/Jones slot. McCarthy definitely would have to appropriately restrict/redefine Zeke's role and handle the RB rotation correctly, but a head coach should be capable of that. If he isn't, there will be other, bigger problems.