It's a bit cliché but the keys to the game will be running the ball (to keep Tampa's pass rush off balance) and stopping the run (to control Tampa's play action game and let our pass rush tee off on Brady).
Brady isn't a guy who is going to just go 5-wide 25 times a game and pick you apart anymore, he's still a really good QB but a lot of their offensive design last year was predicated on play action, so controlling their run game is the key to controlling that. If we can stop the run and force them into obvious passing situations I think Lawrence/Gregory/Parsons could actually make things really difficult for their OL and Brady.
Conversely, Tampa's weak spot on defense is their secondary, if we can keep their pass rush off balance by running the ball I love our chances of hitting some big plays in the passing game. The problem of course is that Tampa has a very stout run defense with Suh/Vea/Gholston.
Offensively I think we should hold our own but I hate how our interior DL matches up with their OL. Lawrence/Gregory/Parsons/Neal can hold their own but I think they'll slowly get worn down as Tampa focuses on the interior run game and working play-action off of it.